Supplementary Figure S23 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

The analysis of single-cell eQTL reveals distinct genetic control mechanisms in colorectal cancer.
Specific risk loci associated with malignant transformation were identified in different cell subtypes.
Colocalization of genetic variants with eQTL suggests a localized effect on gene expression.
Findings enhance understanding of how genetic factors contribute to colorectal cancer progression.

Analysis reveals genetic control of malignant transformation in cell subtypes of colorectal cancer, suggesting subtype-specific risk loci.

Supplementary Figure 23 shows single-cell eQTL colocalization with risk loci of colorectal cancer.

No takes yet. Share an insight, caveat, or question.

Chen et al. (2025) studied this question.

View at Publisher

Ask AI

Bookmark

Share