Supplementary Figure S25 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

MAIN FINDING: The study emphasizes the role of genetic control in colorectal cancer development through single-cell analyses.
KEY EVIDENCE: Supplementary figure presents a design to estimate the genetic risk across diverse ethnic backgrounds.
APPROACH: The methodology includes single-cell eqtl mapping to uncover subtype-specific genetic influences on cancer.
SIGNIFICANCE: These findings can help improve understanding of cancer mechanisms and tailor treatments for various populations.

Supplementary figure analyzes genetic risk of colorectal cancer in multi-ethnic populations, suggesting subtype-specific mechanisms.

Supplementary Figure 25 shows study design to estimate the genetic risk of colorectal cancer in multi-ethnic populations.

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Chen et al. (2025) studied this question.

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