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August 4, 2025

Figure S5 from PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis

Sheue‐Fen Tzeng Yi-Ru Yu Jaeoh Park Janusz von Renesse Huey-Wen Hsiao Chen-Hsuan Hsu Josep Garnica Jintian Chen Lu-Ting Chiu Jonas Santol Tse-Yu Chen Pei-Han Chung Lana E. Kandalaft Patrick Starlinger Cheng‐En Hsieh Ming‐Chin Yu Pei‐Wen Hsiao Santiago J. Carmona Hung-Kai Chen Zhen Meng Yun-Han Lin Jingying Zhou Chin‐Hsien Tsai Ping‐Chih Ho

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Key Points

PLT012 shows significant potential in enhancing antitumor immunity against liver cancer.
In silico analysis indicates effective targeting of metastatic diseases within liver cancer.
Humanized CD36-blocking antibody demonstrated promising effects in preclinical settings.
Findings could lead to improved treatment options for patients with liver cancer and metastasis.

Implication

In silico analysis evaluates PLT012's impact on antitumor immunity in liver cancer, suggesting effective targeting of metastasis.

Abstract

An in silico analysis on POG570 to evaluate the potential of PLT012 in targeting metastatic diseases.

Discussion

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Cite This Study

Tzeng et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0955 https://doi.org/10.1158/2159-8290.29819659

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S1 from PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis2025
2Figure S6 from PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis2025
3Figure S2 from PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis2025
4Figure S3 from PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis2025
5Figure S7 from PLT012, a Humanized CD36-Blocking Antibody, Is Effective for Unleashing Antitumor Immunity Against Liver Cancer and Liver Metastasis2025