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August 15, 2025Open Access

Supplementary Fig. S6 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy

Andreas G. Hadjigeorgiou Constantinos Harkos Aditya K. Mishra Golnaz Morad Sarah B. Johnson Nadim J. Ajami Jennifer A. Wargo Lance L. Munn Triantafyllos Stylianopoulos Rakesh K. Jain

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Key Points

The gut microbiome significantly affects cancer immunotherapy outcomes, leading to improved response rates.
Model validation with a clinical dataset highlighted crucial microbiome interactions related to immunotherapy.
Mathematical modeling techniques provided insights into the complex relationship between microbiome and cancer treatment efficacy.
Findings support the integration of gut microbiome analysis in personalized cancer immunotherapy approaches.

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Implication

Mathematical modeling reveals the gut microbiome's influence on cancer immunotherapy, validating findings with clinical data.

Abstract

Model validation with clinical dataset.

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Cite This Study

Hadjigeorgiou et al. (2025) studied this question.

synapsesocial.com/papers/68af50a1ad7bf08b1ead8a1a https://doi.org/10.1158/0008-5472.29918651

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S2 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
2Supplementary Fig. S4 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
3Supplementary Information from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
4Supplementary Data from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
5Supplementary Fig. S5 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025

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Supplementary Fig. S1 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
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Supplementary Fig. S3 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025