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August 15, 2025Open Access

Supplementary Data from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy

Andreas G. Hadjigeorgiou Constantinos Harkos Aditya K. Mishra Golnaz Morad Sarah B. Johnson Nadim J. Ajami Jennifer A. Wargo Lance L. Munn Triantafyllos Stylianopoulos Rakesh K. Jain

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Key Points

The gut microbiome significantly influences the effectiveness of cancer immunotherapy, highlighting its role in treatment outcomes.
Mathematical modeling indicates that changes in gut microbiome composition can affect immune responses in cancer patients.
Comprehensive analysis utilized mathematical modeling and association techniques to interpret data related to cancer and microbiome.
Findings suggest that microbiome adaptations may enhance immunotherapy effectiveness, emphasizing the need for personalized approaches.

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Implication

Mathematical modeling reveals the impact of the gut microbiome on cancer immunotherapy, suggesting new treatment strategies.

Abstract

Supplementary raw data of the results of the paper

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Cite This Study

Hadjigeorgiou et al. (2025) studied this question.

synapsesocial.com/papers/68af50a1ad7bf08b1ead8ad5 https://doi.org/10.1158/0008-5472.29918672

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Information from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
2Supplementary Fig. S6 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
3Data from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
4Supplementary Fig. S4 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
5Supplementary Fig. S2 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025

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Supplementary Fig. S1 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
Supplementary Fig. S5 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025
Supplementary Fig. S3 from Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy2025