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This is a In Vitro Study study (also classified as: Animal Study).

August 22, 2025Open Access

Bile Salt Hydrolase Activity in the Food-Derived Strain Levilactobacillus brevis M3R3: Genomic and Functional Characterization

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M3R3 exhibited bile salt hydrolase activity, confirming its functional capacity as a probiotic strain.
Growth was inhibited by taurocholic and taurodeoxycholic acids, revealing an adaptive response to bile salts.
Whole-genome sequencing showed no resistance or virulence genes, highlighting safety for consumption.
Genomic analysis identified two bsh genes linked to bile salt deconjugation, indicating potential health benefits.

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Analysis shows bile salt hydrolase activity in Levilactobacillus brevis M3R3, indicating probiotic potential for health applications.

Agolino et al. (2025) studied this question.

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