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January 1, 2025Emergency Medicine InternationalOpen Access

Early 24‐Hour Changes in Systemic Immune–Inflammation Index Predict Acute Kidney Injury and Mortality in ICU Patients

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Authors

FGF. GaoLYLan YangYCYizhe Chen

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Overview

Retrospective cohort study predicts acute kidney injury and 1-year mortality in ICU patients, indicating SII's clinical relevance.

Key Points

  • A steeper systemic immune-inflammation index slope independently predicts acute kidney injury, highlighting its predictive power.
  • Higher extreme values of SII were linked to reduced 1-year survival in critically ill patients, showing significant implications for care.
  • Assessment involved LASSO logistic regression and Cox proportional hazards models using a large ICU database for robust findings.
  • Analysis demonstrates the nomogram's clinical utility for individualized risk stratification of critical care patients.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68af55d8ad7bf08b1eadc71ahttps://doi.org/10.1155/emmi/4949299
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Systemic Immune-Inflammation Index (SII) as a Predictor of Short-Term Mortality Risk in Sepsis-Associated Acute Kidney Injury: A Retrospective Cohort Study2024 · 5 citations
  2. 2Development and external validation of a systemic immune-inflammation index-based prognostic model for 28-day mortality in sepsis-associated acute kidney injury2026
  3. 3Comparison of SII, NLR, and SIRI for severity stratification and prognosis in sepsis-related acute kidney injury2026
  4. 4Association of systemic immune-inflammation index (SII) with 28-day all-cause mortality in acute heart failure: A retrospective cohort study2026
  5. 5Association between Systemic Immune-inflammation Index and Decreased Kidney Function in Patients with Early Chronic Kidney Disease: A Retrospective Study2024