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September 5, 2025CancersOpen Access

Diagnostic Accuracy of Contrast-Enhanced Ultrasound Compared with Contrast-Enhanced Computed Tomography in the Follow-Up of Hepatocellular Carcinoma Treated with Radiofrequency Ablation

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Authors

GGGiulia GoriSMStefano MazzaCCCarlo Ciccioli

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Overview

Observational analysis compares diagnostic accuracy of CEUS and CECT in HCC patients post-radiofrequency ablation, suggesting CEUS as a reliable alternative.

Key Points

  • CEUS accurately identified all 57 nodules with complete response, while CECT misclassified 4 cases, demonstrating superior performance.
  • CEUS exhibited 68.1% sensitivity and 100% specificity, with an overall diagnostic accuracy of 91.1%, closely matching CECT's metrics.
  • Retrospective analysis involved 55 patients with HCC treated via radiofrequency ablation over five years at a single center in Italy.
  • Findings highlight the potential of CEUS as a complementary tool for assessing therapeutic response in HCC cases.

Cite This Study

Gori et al. (2025) studied this question.

synapsesocial.com/papers/68bb421a2b87ece8dc958616https://doi.org/10.3390/cancers17172808
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma post Transcatheter Arterial Chemoembolization 2024 · 1 citations
  2. 2Evaluation of the effectiveness of contrast-enhanced ultrasound in the diagnosis of early hepatocellular carcinoma: a systematic review2025
  3. 3The use of 3D contrast-enhanced ultrasound in assessing the technical success rate of thermal ablation for hepatocellular Carcinoma: A meta-analysis2026
  4. 4Clinical impact of CEUS on non-characterizable observations and observations with intermediate probability of malignancy on CT/MRI in patients at risk for HCC2024 · 12 citations
  5. 5The Role of Sonazoid-contrast-enhanced Ultrasound In Precision Diagnosis and Guidance for Radiofrequency Ablation Therapy of Hepatocellular Carcinoma: a Literature Review2026 · 1 citations