Table S5 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30028694

Key Points

Dietary fiber shows variable effects on immune checkpoint blockade efficacy across different murine tumor models.
In the B16-OVA model, serum metabolite levels indicate a lack of consistent response to dietary fiber intervention.
This assessment involves analyzing serum metabolite peak areas in murine tumor models to evaluate dietary fiber effects.
The findings challenge assumptions about dietary fiber's role in enhancing immune therapy, indicating further exploration is needed.

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Implication

Analysis shows inconsistent effects of dietary fiber on immune checkpoint blockade in murine tumor models, suggesting variability in treatment outcomes.

Abstract

Serum metabolite peak areas from the B16-OVA model

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Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd028da https://doi.org/10.1158/0008-5472.30028694

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Table S5 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S5 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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