Table S5 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30029845

Key Points

Immune checkpoint blockade efficacy does not consistently change with dietary fiber across murine models.
Serum metabolite peak areas from the B16-OVA model indicate distinct metabolic responses.
Observational analysis of diverse murine tumor models highlights the variability in dietary impact.
Findings suggest dietary strategies may have limited effects on enhancing immune responses to therapy.

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Implication

Analysis reveals dietary fiber has no consistent effect on immune checkpoint blockade efficacy in murine tumor models, pointing to potential limitations in dietary strategies.

Abstract

Serum metabolite peak areas from the B16-OVA model

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Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f076d6d5674bcd02b80 https://doi.org/10.1158/0008-5472.30029845

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Table S5 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S5 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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