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September 5, 2025Carleton undergraduate journal of science.Open Access

Working Memory Dysfunction: An fMRI Analysis in Schizophrenia

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Authors

JBJana Marguerite BennettRHRami HamatiZSZacharie Saint-Georges

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Overview

This analysis demonstrates impaired brain activation during working memory tasks in schizophrenia, suggesting cognitive deficits.

Key Points

  • Individuals with schizophrenia showed significantly lower accuracy on the n-back task, indicating cognitive deficits.
  • During the fMRI analysis, greater activation in the default mode network was found in those with schizophrenia, reflecting working memory issues.
  • The analysis compared brain activation patterns between individuals with schizophrenia and healthy controls during working memory tasks.
  • Understanding these brain activation differences is crucial for identifying risk markers and developing treatment plans for memory symptoms.

Cite This Study

Bennett et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f7a6d6d5674bcd03bf0https://doi.org/10.22215/cujs.v5i1.5298
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Origins of Spatial Working Memory Deficits in Schizophrenia: An Event-Related fMRI and Near-Infrared Spectroscopy Study2008 · 108 citations
  2. 2THE ROLE OF THALAMIC CONNECTIVITY IN WORKING MEMORY IMPAIRMENT IN SCHIZOPHRENIA: MERGING EVIDENCE FROM FMRI AND EEG2021
  3. 3Tale of Two <i>n</i> ‐Backs: Diverging Associations of Dorsolateral Prefrontal Cortex Activation With <i>n</i> ‐Back Task Performance2025 · 2 citations
  4. 4Cognitive modes underlying attentional control impairments in schizophrenia: an fMRI study2025
  5. 5Widespread Cortical Dysfunction in Schizophrenia: The FBIRN Imaging Consortium2008 · 71 citations