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Co-culture findings demonstrate that TRAF3IP2-AS1 deficiency enhances EMT via macrophage-derived TGFβ1, suggesting a mechanism for tumor progression.
Supplementary Fig. S5 In co-culture with macrophages, TRAF3IP2-AS1 deficiency-induced necroptosis promotes the enhancement of EMT via the secretion of TGFβ1.
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Wu et al. (2025) studied this question.
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