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September 4, 2025Open Access

Supplementary Figure S11 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors

Min Wang Yanxing Chen Lin Tian Chenyi Wu Jiaying Chen Jiajia Hu Runjie Huang Yingnan Wang Jinling Zhang Xiaojun Ouyang Liqin Wang Ying Jin Qi Zhao Feng Wang Rui‐Hua Xu

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Key Points

Vascular normalization enhances antitumor efficacy when combined with HDAC inhibitors and immunotherapy in solid tumors.
The analysis utilized flow cytometry to differentiate various cell subpopulations relevant to treatment outcomes.
A comprehensive focus on cellular interactions in the tumor microenvironment enhances understanding of therapy effectiveness.
Findings suggest that improving blood vessel function could be pivotal for the success of combined cancer therapies.

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Implication

Observational analysis shows improved antitumor efficacy in solid tumors with vascular normalization, indicating better therapy outcomes.

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Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c18c089b7b07f3a061489a https://doi.org/10.1158/2159-8290.30050811

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S10 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
2Supplementary Figure S6 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
3Supplementary Figure S2 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
4Supplementary Figure S1 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
5Supplementary Figure S3 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
6Supplementary Figure S9 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
7Supplementary Figure S7 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
8Supplementary Figure S5 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025