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This is a Meta-Analysis study (also classified as: Systematic Review).

Deep brain stimulation for treatment-resistant major depressive disorder: a network meta-analysis of stimulation targets

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Stimulation of the medial forebrain bundle led to the greatest reduction in depressive symptoms, indicating its potential superiority.
The most notable responder rate (86%) was observed with the medial forebrain bundle compared to other stimulation targets.
This systematic literature review encompassed 22 trials, predominantly sham-controlled, securing a robust evaluation of treatment-resistant depression interventions.
Further trials are necessary to validate the medial forebrain bundle as the optimal target for neurostimulation in major depressive disorder.

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Systematic review compares deep brain stimulation targets in reducing depressive symptoms, suggesting optimal efficacy of medial forebrain bundle.

Naik et al. (2025) studied this question.

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Systematic review compares deep brain stimulation targets in reducing depressive symptoms, suggesting optimal efficacy of medial forebrain bundle.