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September 10, 2025Journal of Materials Chemistry B

BODIPY-Based Fluorescent Probes Distinguish the Heterogeneity of Lipid Droplets in Carotid and Femoral Atherosclerotic Plaques

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Authors

BJBiao JingJGJinting GeCWChengxin Weng

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Overview

Fluorescent probes track lipid droplets in atherosclerotic plaques, indicating organ-specific characteristics.

Key Points

  • Probes successfully distinguished lipid droplet heterogeneity in atherosclerotic plaques from various vascular regions.
  • Fluorescent sensors exhibited detection limits as low as 50 μg mL-1 for lipids, enhancing plaque assessment.
  • The methods included ex vivo imaging in ApoE-/- mice and human tissue samples, revealing unique lipid profiles.
  • The findings suggest potential applications in understanding disease pathogenesis and assessing plaque stability.

Cite This Study

Jing et al. (2025) studied this question.

synapsesocial.com/papers/68c1a27254b1d3bfb60ddc11https://doi.org/10.1039/d5tb01392e
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