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September 15, 2025

Figure S6 from Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells

Guangqin Liu Haoqian Zhang Siqi Chen Jun Gao Haixin Zhao Yan Dong Changwei Liu Xuechen Wei Ting Li Chang Lu Hai-Zhen Zhu Dingyi Lu Shiyu Feng Teng Li Weina Zhang Qing Xia Jianghong Man Tao Zhou Jiayi Chen Ailing Li Xin Pan

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Key Points

Evaluation of berberine shows promise for glioblastoma treatment, indicating a potential new direction for therapy.
Findings emphasize the role of mitochondrial calcium uniporter in regulating acetyl-coa metabolism impacting glioblastoma stem cells.
Safety assessments of berberine highlight its viability for further research in glioblastoma clinical applications.
Integration of acetyl-coa metabolism and h3k27 acetylation processes could open pathways for novel cancer therapies.

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Implication

Assessment reveals potential of berberine in managing acetylation processes in glioblastoma stem cells, suggesting treatment avenues.

Abstract

Figure S6 shows safety assessment of berberine for GBM treatment.

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Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68d4508931b076d99fa588ad https://doi.org/10.1158/0008-5472.30125821

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S4 from Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells2025
2Figure S2 from Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells2025
3Figure S3 from Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells2025
4Figure S1 from Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells2025
5Figure S5 from Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells2025

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