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Liver pH imaging for diagnosis and prognosis

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This method maps pHe in mouse liver tumors at 0.6mm resolution, highlighting immune dynamics and acidity in the tumor microenvironment.

Feasibility of pHe imaging with reduced spherical encoding was demonstrated in a liver tumor model.
Mapping pHe at submillimeter resolution revealed critical insights into the tumor microenvironment.
High-resolution imaging using RESEGAW allows precise metabolic characterization of liver tumors.
This approach may enhance the understanding of immune dynamics in relation to TME acidity.

Santana et al. (2025) studied this question.

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