Live imaging reveals BBOX1 as a key metabolic checkpoint that influences cancer cell evasion from NK cells, suggesting potential therapeutic targets.
Live imaging of coculture of mouse splenic NK cells (green border line) and Renca-derived BBOX1pos cells (white border line) with BBOX1 knockdown (BBOX1 KD) when in the absence or presence of carnitine.
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Zhang et al. (2025) studied this question.
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