Table S1 from Vγ9Vδ2 T Cells Express an Antitumor Profile Associated with Anti–PD-(L)1 Responses and Activation Defects Restored by Anti-BTN3A in Triple-Negative Breast Cancer

Q: What type of study is this?

This is a Quantitative Study study.

Stéphane Fattori; Laurent Gorvel; Marie-Sarah Rouvière; Samuel Granjeaud; Amira Ben Amara; Manon Richaud; Nicolas Boucherit; Carole Tarpin; Jihane Pakradouni; Julien Hédou; Grégoire Bellan; Brice Gaudillière; Emmanuelle Charafe‐Jauffret; Gilles Houvenaeghel; Éric Lambaudie; François Bertucci; Jean‐Jacques Fournié; Anthony Gonçalvès; Philippe Rochigneux; Anne-Sophie Chrétien; Daniel Olive

doi:10.1158/2326-6066.30255226

Key Points

Vγ9Vδ2 T cells demonstrate an antitumor profile associated with anti–PD-(L)1 responses in triple-negative breast cancer.
The study identifies activation defects in these T cells, which can be restored by anti-BTN3A treatment.
Patient profiling involved detailed clinical characteristics, emphasizing the relevance of T cell characterization in cancer treatment.
Significant implications arise for enhancing immune responses against breast cancer through targeted therapies.

Implication

Analysis shows that vγ9vδ2 t cells exhibit an antitumor profile in triple-negative breast cancer, suggesting potential therapeutic implications involving anti–pd-(l)1.

Abstract

Clinical characteristics of patients with breast cancer & studies ID for Vg9Vd2 T cell profiling

Discussion

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Cite This Study

Fattori et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21a8d https://doi.org/10.1158/2326-6066.30255226

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Table S1 from Vγ9Vδ2 T Cells Express an Antitumor Profile Associated with Anti–PD-(L)1 Responses and Activation Defects Restored by Anti-BTN3A in Triple-Negative Breast Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Table S1 from Vγ9Vδ2 T Cells Express an Antitumor Profile Associated with Anti–PD-(L)1 Responses and Activation Defects Restored by Anti-BTN3A in Triple-Negative Breast Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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