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September 3, 2024Journal of the American Chemical Society

Development of Integrin-Facilitated Bispecific Aptamer Chimeras for Membrane Protein Degradation

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Authors

WSWeidi SunHZHui ZhangWXWanlin Xie

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Sun et al. (2024) studied this question.

synapsesocial.com/papers/68e5969fb6db643587531febhttps://doi.org/10.1021/jacs.4c04794
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Also Consider

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  1. 1Development of Integrin Targeting Chimeras (ITACs) for the Lysosomal Degradation of Extracellular Proteins2024 · 18 citations
  2. 2Multivalent Aptamer‐Based Lysosome‐Targeting Chimeras (LYTACs) Platform for Mono‐ or Dual‐Targeted Proteins Degradation on Cell Surface2024 · 67 citations
  3. 3Lysosome‐Targeting Chimeras (LYTACs): From Modular Design Principles to Diverse Therapeutic Applications2026 · 1 citations
  4. 4Circular Bivalent Aptamer Chimeras Leveraging LDLR-Mediated Lysosomal Shuttling for Targeted Protein Degradation2026
  5. 5Applications of Lysosome‐Targeting Receptors (LTRs) in Targeted Protein Degradation2025