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February 29, 2024Advanced ScienceOpen Access

Multivalent Aptamer‐Based Lysosome‐Targeting Chimeras (LYTACs) Platform for Mono‐ or Dual‐Targeted Proteins Degradation on Cell Surface

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Authors

QDQiao DuanHJHao‐Ran JiaWCWeichang Chen

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Cite This Study

Duan et al. (2024) studied this question.

synapsesocial.com/papers/68e76cedb6db6435876e2871https://doi.org/10.1002/advs.202308924
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lysosome‐Targeting Chimeras (LYTACs): From Modular Design Principles to Diverse Therapeutic Applications2026 · 1 citations
  2. 2Lysosome‐Mediated Targeted Protein Degradation: Emerging Chimeric Platforms for Extracellular and Intracellular Therapeutics2025
  3. 3Applications of Lysosome‐Targeting Receptors (LTRs) in Targeted Protein Degradation2025
  4. 4Development of Integrin-Facilitated Bispecific Aptamer Chimeras for Membrane Protein Degradation2024 · 47 citations
  5. 5Programming DNA Nanoassemblies into Polyvalent Lysosomal Degraders for Potent Degradation of Pathogenic Membrane Proteins2024 · 9 citations