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May 1, 2024ImmunobiologyOpen Access

Activation of the cGAS-STING pathway by viral dsDNA leading to M1 polarization of macrophages mediates antiviral activity against hepatitis B virus

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QZQiyin ZongAnhui Medical UniversityHZHao ZhangHengshui UniversityFLFuting LiuAnhui Medical University

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Cite This Study

Zong et al. (2024) studied this question.

synapsesocial.com/papers/68e6c052b6db6435876402a9https://doi.org/10.1016/j.imbio.2024.152810
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Also Consider

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  1. 1Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages2024 · 14 citations
  2. 2Impairment of Rab7-dependent STING degradation hampers HBV replication but accelerates disease progression in chronic hepatitis B comorbid with MASLD2026 · 2 citations
  3. 3Antiviral and immune modulatory activities of STING agonists in a mouse model of persistent hepatitis B virus infection2025
  4. 4Antiviral and immune modulatory activities of STING agonists in a mouse model of persistent hepatitis B virus infection2025
  5. 5HBV induces immunosuppressive macrophages via metabolic and epigenetic reprogramming to facilitate the establishment of chronic persistent infection2026