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October 20, 2025International Journal of EndocrinologyOpen Access

Therapeutic Potential of Cynara scolymus Extract and Bifidobacterium longum in Alleviating Diabetes‐Induced Male Reproductive Dysfunction

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Authors

HBHadis bozorgpoursavadjaniHKHaniyeh KeyghobadiDMDelaram Moghadam

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Overview

Combination therapy with cynara scolymus and bifidobacterium longum substantially improves male reproductive health in diabetic rats, suggesting potential clinical applications.

Key Points

  • Combined treatment with cynara scolymus and bifidobacterium longum results in significant improvements in male reproductive hormone levels.
  • Diabetic rats receiving both treatments exhibited reduced fasting blood sugar and malondialdehyde levels compared to untreated diabetic controls.
  • Histological evaluations showed enhanced testicular architecture in rats treated with the combined therapy, indicating better reproductive health.
  • The methodology involved inducing diabetes in male rats and assessing various reproductive health parameters and hormone levels.

Cite This Study

bozorgpoursavadjani et al. (2025) studied this question.

synapsesocial.com/papers/68f5fcdc8d54a28a75cf22c6https://doi.org/10.1155/ije/5884930
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Investigating the stereological and oxidative stress effects of hydroalcoholic extracts of <i>Cynara scolymus</i> L. and pioglitazone on diabetic rat ovary2026
  2. 2Protective mechanisms of the brown alga Cystoseira myrica supplementation against testicular alterations in streptozotocin-induced diabetic rats2026
  3. 3Triple Actions of a Novel Polyherbal JDED Formulation Restores Glycemic and Reproductive Function in Diabetic Male Rats Via Antioxidant, Hormonal and Metabolomic Modulation2025
  4. 4Red rice bran extract attenuates oxidative stress and testicular damage in high-fat diet/streptozotocin-induced diabetic rats2025
  5. 5Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, <i>Garcinia kola</i> , and <i>Momordica charantia</i> in Rats2026