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December 8, 2025BloodOpen Access

The unseen bleed- temporal and demographic patterns of thrombocytopenia mortality in the United States: A 25-year analysis of the CDC wonder database

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BFBolivia Fernandes

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Overview

Analysis reveals rising mortality rates in thrombocytopenia, particularly in non-metropolitan areas, suggesting targeted interventions are necessary.

Key Points

  • To analyze the trends and demographic patterns of mortality related to thrombocytopenia in the United States over 25 years.
  • Utilized CDC WONDER database to obtain Age-adjusted Mortality Rates
  • Employed ICD-10 Codes for Thrombocytopenia
  • Applied Joinpoint regression for Annual percent Change calculations
  • 158,739 thrombocytopenia-related deaths from 1999 to 2023
  • Overall mortality rose from 2.6 in 1999 to 4.0 in 2023
  • Males had higher AAMR than females (3.4 vs 2.3)
  • NH Blacks and non-metropolitan areas had the highest mortality rates

Cite This Study

Bolivia Fernandes (2025) studied this question.

synapsesocial.com/papers/69362f5d4fa91c937236dbc0https://doi.org/10.1182/blood-2025-6595
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Also Consider

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  3. 3Hemostasis in crisis: Two-decade trends of mortality due to coagulation defects in the u.S. population; A CDC- wonder database analysis2025
  4. 4Thrombotic thrombocytopenic purpura-related mortality trends among the United States population: A retrospective study using the CDC wonder database2025
  5. 5Trends in thromboembolism-related mortality among patients with hematologic malignancies in the u.S., 1999–2023: A CDC wonder analysis2025 · 1 citations