Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Changing burden of Acute Myeloid Leukemia in the United States: A 23-year national analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

OJOmer Jamy

Discussion

Loading...

Member takes

Overview

National analysis reveals declining incidence and mortality for acute myeloid leukemia, highlighting health equity issues across demographics.

Key Points

  • This analysis aims to characterize the burden of acute myeloid leukemia (AML) in the US over 23 years. It evaluates changes in incidence and mortality, considering demographic and geographic factors.
  • Utilized CDC WONDER Cancer Statistics database for incidence and mortality data from 1999-2021.
  • Stratified data by age, gender, race/ethnicity, and geography.
  • Calculated age-adjusted incidence rates (AAIR) and mortality rates (AAMR); assessed trends with Joinpoint Regression.
  • From 1999 to 2021, 291,049 new AML cases and 207,713 deaths were recorded.
  • Significant mortality-to-incidence ratio decline observed in young adults, while older adults showed minimal improvement.
  • Geographic analysis revealed varying trends, with Minnesota showing the most significant reductions.

Cite This Study

Omer Jamy (2025) studied this question.

synapsesocial.com/papers/69362f5d4fa91c937236dbf1https://doi.org/10.1182/blood-2025-6399
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of sociodemographic factors on survival outcomes in chronic myeloid leukemia in the United States: A time-trend analysis2025
  2. 2Acute Myeloid Leukemia mortality in u.S. older adults: A 45-year nationwide analysis with forecasting through 20502025
  3. 3Demographics and trends of acute myeloid leukemia among young adults in the United States and Puerto Rico, 1999-2021.2026
  4. 4Comparative analysis of mortality trends in acute versus chronic myeloid leukemia in the U.S. population with time series projection: A CDC WONDER–based study (1999–2023).2026
  5. 5Comparative trends in mortality from acute lymphoblastic and Acute Myeloid Leukemia in the United States: A CDC wonder analysis (1999–2020)2025