What question did this study set out to answer?

December 8, 2025Blood

Impact of sociodemographic factors on survival outcomes in chronic myeloid leukemia in the United States: A time-trend analysis

View Full Paper

Ask AI

Bookmark

Authors

Time-trend analysis shows CML survival improved significantly, indicating impacts of age and geographic variation influenced by access to care.

The aim is to assess the impact of sociodemographic factors on survival outcomes in chronic myeloid leukemia in the U.S.
Analyzed CML incidence and mortality data from CDC WONDER 1999–2021
Stratified data by age, gender, race/ethnicity, region, and state
Calculated Age-Adjusted Mortality Rates (AAMR) and Incidence Rates (AAIR)
Utilized Joinpoint Regression to assess survival trend changes
Overall AAIR increased from 2.19 to 2.64, while AAMR declined from 0.90 to 0.41
Marked survival gains observed, especially in young adults with significant AAMR reductions
Improvements noted across all racial groups, with varying success by state and region

Ravi Bhatia (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Time-trend analysis shows CML survival improved significantly, indicating impacts of age and geographic variation influenced by access to care.