Exercise training significantly improved peak oxygen uptake in older HFpEF patients without type 2 diabetes, but had less impact on those with diabetes.
Does exercise training improve peak oxygen uptake and 6-minute walk distance in older HFpEF patients with and without type 2 diabetes mellitus?
Exercise training yields divergent effects on exercise capacity in older HFpEF patients, with blunted improvements in peak oxygen uptake but preserved gains in 6-minute walk distance among those with concurrent type 2 diabetes.
Absolute Event Rate: 0% vs 0%
Reduced exercise capacity is a hallmark of heart failure with preserved ejection fraction (HFpEF), and this limitation is particularly pronounced in older patients with coexisting type 2 diabetes mellitus (T2DM), a high-risk population characterized by poor prognosis. Although previous studies have demonstrated that exercise training (ET) can improve exercise capacity in patients with HFpEF, its efficacy in older patients with coexisting HFpEF and T2DM remains unclear. Therefore, we evaluated the effects of ET on peak oxygen uptake (peakVO
Sugita et al. (Mon,) reported a other. Exercise training significantly improved peak oxygen uptake in older HFpEF patients without type 2 diabetes, but had less impact on those with diabetes.
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