What does this research mean for the field?

Mid-term survival after coronary endarterectomy with CABG is acceptable despite notable early morbidity and mortality. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To analyze outcomes and identify determinants of coronary endarterectomy combined with CABG.

January 10, 2026Cureus0 citationsOpen Access

Outcomes and Determinants of Coronary Endarterectomy With Coronary Artery Bypass Graft (CABG): A Tertiary Centre’s Five-Year Experience

NANada AliUniversity of Liverpool FGFrancesca Gatta MEMahmoud ElkhatibUniversity of Liverpool

Key Result

Mid-term survival after coronary endarterectomy with CABG is acceptable despite notable early morbidity and mortality.

Key Points

To analyze outcomes and identify determinants of coronary endarterectomy combined with CABG.
Retrospective review of surgical cases at a tertiary centre
Assessment of early morbidity and mortality rates
Evaluation of vessel- and technique-specific risks
Analysis of perioperative protocols and antithrombotic strategies
Notable early morbidity and mortality observed
Acceptable mid-term survival rates reported
Identification of specific risks based on surgical techniques and vessels involved
Need for larger studies indicated to improve patient selection and surgical standards

Structured PICO

Population

48 patients with severe diffuse coronary artery disease who underwent isolated urgent or elective coronary artery bypass grafting (CABG) combined with coronary endarterectomy (CE-CABG). Mean age 66.5 ± 9.1 years, 81.3% male, UK-based (single tertiary centre). Excluded: patients with concomitant cardiac procedures or incomplete records.

Intervention

Coronary endarterectomy (CE) combined with coronary artery bypass grafting (CABG), performed via open or closed technique.

Outcome

Short- and mid-term survival (early/operative mortality and mid-term survival up to 5 years)hard clinical

CE-CABG carries a notable early mortality risk but provides acceptable mid-term survival and symptomatic relief for patients with diffuse coronary artery disease unsuitable for conventional CABG.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

CE-CABG carries notable early morbidity and mortality, but mid-term survival remains acceptable. This study highlights vessel- and technique-specific risk, though the limited statistical power and absence of standardised perioperative protocols constrain generalisability. Larger studies are needed to refine patient selection, optimise surgical approach, and standardise antithrombotic strategies following CE.

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