Review analyzes synthesis methods and properties of thiomorpholines, indicating ongoing developments in thiomorpholine chemistry.
The review analyzes literature data published mainly over the past 10–15 years on the synthesis and properties of thiomorpholines, primarily new methods for constructing the thiomorpholine ring and new aspects of the chemistry of thiomorpholines. The formation of thiomorpholine derivatives from sulfur dichloride and primary or secondary amines, 2-aminoethanethiol, and other S,N-containing initial compounds is considered.
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Makhaeva et al. (2025) studied this question.
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