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March 8, 2026Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

Multidimensional Regulatory Network of YAP1 Driving Malignant Progression in Esophageal Cancer: Molecular Mechanisms and Targeted Therapy: A Review

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Authors

JCJunhui ChenSDSi-Run DuCLChang Liu

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Overview

Review highlights yap1's roles in apoptosis and metastasis in esophageal cancer, suggesting precision medicine strategies.

Key Points

  • To summarize the regulatory network of yap1 and its implications in esophageal cancer.
  • Systematic review of multi-omics research
  • Analysis of molecular mechanisms and activation pathways
  • Evaluation of therapeutic strategies and roles in treatment resistance
  • YAP1 plays critical roles in esophageal cancer progression and therapeutic resistance
  • Identified potential as a diagnostic, prognostic, and predictive biomarker
  • Emphasized the need for selective inhibitors and precision medicine approaches

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69acc57d32b0ef16a404fb87https://doi.org/10.32604/or.2026.073484
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1YAP as a therapeutic target in esophageal squamous cell carcinoma: insights and strategies2025
  2. 2The potential relationship between YAP and PCNP in esophageal carcinoma and its influence on carcinogenesis2025
  3. 3Epithelial-Mesenchymal Transition Activates YAP to Drive Malignant Progression and Immune Evasion2025 · 1 citations
  4. 4YAP1 in control: how RNA networks and protein modifications shape its function and therapeutic targetability2026
  5. 5Epithelial-Mesenchymal Transition Activates YAP to Drive Malignant Progression and Immune Evasion2025 · 1 citations