Key result
High Lp(a) in children is strongly linked to parental CVD and familial hypercholesterolemia.
Why the study?
Are Lipoprotein(a) levels in children and adolescents associated with parental cardiovascular disease, familial hypercholesterolemia, and gender differences?
Meta-Analysis
Are Lipoprotein(a) levels in children and adolescents associated with parental cardiovascular disease, familial hypercholesterolemia, and gender differences?
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The findings support targeted Lipoprotein(a) assessment in children with familial cardiovascular risk using ancestry-aware reference standards.
Dholariya et al. (2026) conducted a meta-analysis in Elevated Lipoprotein(a). Parental cardiovascular disease and familial hypercholesterolemia was evaluated on Lipoprotein(a) levels. Elevated Lipoprotein(a) in children was strongly associated with parental cardiovascular disease and modestly elevated in familial hypercholesterolemia, with prominent ethnic variation.
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