January 1, 2015Journal of Cardiovascular Magnetic ResonanceOpen Access

Clinical experience of strain imaging using DENSE for detecting infarcted cardiac segments

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Why the study?

Does DENSE-derived strain imaging accurately detect infarcted cardiac segments in patients with suspected coronary artery disease?

Population

125 patients with suspected coronary artery disease, including 57 with scar area >1% in at least one…

Comparison

Displacement Encoding with Stimulated Echoes… vs Late gadolinium enhancement MRI for the…

Design

Cross-sectional

Authors

JKJohan KihlbergLinköping University HHHenrik HaraldssonUniversity of California, San Francisco ASAndreas SigfridssonCardiac Imaging

Discussion

Member takes

Implication

May aid infarct detection in suspected CAD; hypothesis-generating for DENSE strain pending prospective validation.

Structured PICO

Does DENSE-derived strain imaging accurately detect infarcted cardiac segments in patients with suspected coronary artery disease?

Population

125 patients (29 women and 96 men) with suspected coronary artery disease, including 57 with scar area >1% in at least one segment, 23 free from CAD (control group), and 45 with pathological findings but no scar.

Intervention

Displacement Encoding with Stimulated Echoes (DENSE) magnetic resonance imaging to calculate left ventricular strain (radial, circumferential, and longitudinal).

Comparator

Late gadolinium enhancement (LGE) MRI for the detection of myocardial scar.

Outcome

Detection of 50% transmurality (myocardial scar).surrogate

DENSE-derived circumferential strain is highly accurate and reproducible for detecting myocardial segments with >50% scar area in patients with suspected coronary artery disease.

Cite This Study

Kihlberg et al. (2015) studied this question.

synapsesocial.com/papers/69c4314872b72c512082a2c0 https://doi.org/10.1186/s12968-015-0155-8

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Clinical experience of strain imaging using DENSE for detecting infarcted cardiac segments

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Clinical experience of strain imaging using DENSE for detecting infarcted cardiac segments

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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