Population
Cardiac myocytes (in vivo intact heart and primary cultures)
Design
Review
Authors
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Ras and Akt pathways remain hypothesis-generating for cardiac hypertrophy; leaves open mechanoreception mechanisms without supporting clinical translation.
Ras and Akt signaling pathways are likely involved in cardiac myocyte mechanotransduction and hypertrophy, though further research is required to fully elucidate the mechanisms.
Peter H. Sugden (2003) studied this question.
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