Association of Blood Pressure Responses to Submaximal Exercise in Midlife With the Incidence of Cardiovascular Outcomes and All‐Cause Mortality: The Framingham Heart Study
Why the study?
Few studies have examined the associations of midlife blood pressure responses to submaximal exercise with the risk of cardiovascular outcomes and mortality in later life.
Do blood pressure responses to submaximal exercise in midlife predict the incidence of cardiovascular outcomes and all-cause mortality?
Population
1993 Framingham Offspring Study participants attending examination cycle 7
Comparison
Blood pressure responses and BP recovery following submaximal exercise
Design
Prospective cohort study
Authors
Discussion
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Member takes
Implication
Impaired BP recovery after submaximal exercise may flag higher midlife hypertension and CVD risk; hypothesis-generating and requires prospective validation.
Structured PICO
Do blood pressure responses to submaximal exercise in midlife predict the incidence of cardiovascular outcomes and all-cause mortality?
P
Population
1993 Framingham Offspring Study participants (mean age, 58 years; 53.2% women) attending examination cycle 7.
I
Intervention
Blood pressure (BP) responses to submaximal exercise (exercise BP and rapid BP recovery)
O
Outcome
Incidence of hypertension, cardiovascular disease (CVD), and all-cause mortality, and prevalent subclinical CVD (left ventricular mass and carotid intima-media thickness)hard clinical
Higher submaximal exercise BP and impaired BP recovery in midlife are associated with increased risk of subclinical CVD, incident hypertension, clinical CVD, and all-cause mortality.
Cite This Study
Lee et al. (2020) studied this question.