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April 11, 2017Hypertension

Brain Renin–Angiotensin System

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Authors

BTBibi S. van ThielErasmus MC AMAlexandre MartiniUniversidade de Brasília LRLuuk te RietErasmus MC

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Implication

Brain renin largely plasma-derived in mice; leaves open independent brain RAS in human hypertension.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Thiel et al. (2017) studied this question.

synapsesocial.com/papers/69d89250d56ca42147d18d1e https://doi.org/10.1161/hypertensionaha.116.08922

Topics

Hypertension management

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Studies on angiotensinogen of plasma and cerebrospinal fluid in normal and hypertensive human subjects.1980 · 44 citations
2Nephrectomy, converting enzyme inhibition, and angiotensin peptides.1993 · 181 citations
3Chronic Increases in Circulating Prorenin Are not Associated With Renal or Cardiac Pathologies2009 · 80 citations
4Adrenal Angiotensin: Origin and Site of Generation2005 · 39 citations
5Preservation of Intracellular Renin Expression Is Insufficient to Compensate for Genetic Loss of Secreted Renin2009 · 43 citations