This review shows how Y-90 radioembolization improves outcomes in hepatocellular carcinoma, suggesting new treatment potentials for transplant eligibility.
Key Points
The aim is to evaluate the effectiveness of Y-90 radioembolization for downstaging and bridging hepatocellular carcinoma patients to liver transplantation.
Review of pivotal studies such as LEGACY and DOSISPHERE-01.
Comparison of Y-90 with transarterial chemoembolization.
Evaluation of treatment planning and multidisciplinary coordination.
Y-90 demonstrates high rates of sustained tumor response.
Low dropout rates from the transplant list are observed.
Enhanced post-transplant survival, particularly with segmental delivery and personalized dosimetry.