April 1, 2016Circulation Cardiovascular Imaging127 citationsOpen Access

Prospective Evaluation of 18 F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome

CRChristoph RischplerCardiac Imaging RDRalf J. DirschingerUniversity of London SNStephan G. NekollaUniversity of Hohenheim

Structured PICO

Does 18F-FDG uptake measured by simultaneous PET/MRI predict functional outcome at 6 months in patients after acute myocardial infarction?

Population

Patients after acute myocardial infarction

Intervention

Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) to evaluate 18F-Fluorodeoxyglucose (18F-FDG) uptake

Outcome

Functional outcome at 6 monthssurrogate

18F-FDG uptake in infarcted myocardium evaluated by PET/MRI may represent a novel biosignal of myocardial injury that inversely correlates with functional outcome.

Abstract

In this study, the intensity of (18)F-FDG uptake in the myocardium after acute myocardial infarction correlated inversely with functional outcome at 6 months. Thus, (18)F-FDG uptake in infarcted myocardium may represent a novel biosignal of myocardial injury.

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