To investigate how free calcium affects calcium release from the sarcoplasmic reticulum in muscle cells.
Examined skinned skeletal muscle fibers immersed in low magnesium ion solutions.
Analyzed calcium release dynamics from the sarcoplasmic reticulum.
Free calcium effectively triggers the release of stored calcium.
Calcium release observed even in low magnesium concentration conditions.
Abstract
Free calcium appears to trigger the release of stored calcium from the sarcoplasmic reticulum of skinned skeletal muscle fibers immersed in solutions with a low concentration of magnesium ion.