3D transoesophageal echocardiography demonstrates that left atrial dilatation causes mitral valve annulus enlargement and reduced leaflet co-aptation, leading to atrial mitral regurgitation independent of left ventricular dilatation.
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May identify atrial MR mechanism in isolated LA enlargement; leaves open need for prospective studies on management implications.
LA dilatation leads to MVA enlargement, reduced leaflet co-aptation and MR even without LV dilatation. A co-aptation index describes this in vivo. This work provides insights into the mechanism of AMR.
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Ring et al. (2013) studied this question.
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