What question did this study set out to answer?

To investigate the relationship between myocardial tissue changes and nailfold capillaroscopy patterns in patients with systemic sclerosis.

April 30, 2026Lara D. Veeken

P130 Subclinical myocardial tissue changes in systemic sclerosis associate with progressive nailfold capillaroscopy patterns

View Full Paper

Ask AI

Bookmark

To investigate the relationship between myocardial tissue changes and nailfold capillaroscopy patterns in patients with systemic sclerosis.
SSc patients without ischaemic heart disease or major cardiovascular risk factors underwent CMR and NFC assessments.
NFC patterns were classified as non-specific, early, active, or late.
Abnormal myocardial tissue was defined by specific CMR criteria including non-ischaemic late gadolinium enhancement and elevated native T1.
Fifty percent of patients exhibited abnormal CMR findings, with varying frequencies across NFC patterns.
Active and late NFC patterns were associated with diffuse myocardial fibrosis in systemic sclerosis patients.
NT-proBNP levels increased across all NFC groups, indicating progressive myocardial strain.

Authors

CSCristiana Sieiro SantosManchester Academic Health Science Centre RDRaluca B DumitruUniversity Hospital Coventry GAGiuseppina AbignanoUniversity of Basilicata

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Observational findings reveal subclinical myocardial tissue changes in systemic sclerosis, suggesting progressive fibrosis and linking cardiac pathology with nailfold capillaroscopy patterns.

Cite This Study

Santos et al. (2026) studied this question.

synapsesocial.com/papers/69f2a4b78c0f03fd67763cc5 https://doi.org/10.1093/rheumatology/keag121.164

View Full Paper

Ask AI

Bookmark

Implication

Observational findings reveal subclinical myocardial tissue changes in systemic sclerosis, suggesting progressive fibrosis and linking cardiac pathology with nailfold capillaroscopy patterns.

P130 Subclinical myocardial tissue changes in systemic sclerosis associate with progressive nailfold capillaroscopy patterns

Key Points

Discussion

Implication

Cite This Study

P130 Subclinical myocardial tissue changes in systemic sclerosis associate with progressive nailfold capillaroscopy patterns

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider