Key result
Systemic sclerosis patients without cardiac symptoms had significantly lower mean peak radial and circumferential strain compared to healthy controls (p=0.011 and p=0.003, respectively).
Why the study?
Does complementary CMR detect subclinical left ventricular regional dysfunction and myocardial abnormalities in asymptomatic patients with systemic sclerosis compared to healthy controls?
Population
25 subjects total: 15 consecutive patients with systemic sclerosis without cardiac symptoms and 10 healthy…
Comparison
Complementary cardiac magnetic resonance imaging… vs Healthy controls undergoing the same CMR protocol.
Design
Case-control
Authors
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May signal early cardiac involvement in systemic sclerosis; hypothesis-generating for strain imaging before clinical adoption.
Cross-Sectional (n=25)
No
Does complementary CMR detect subclinical left ventricular regional dysfunction and myocardial abnormalities in asymptomatic patients with systemic sclerosis compared to healthy controls?
p-value: p=0.011 and 0.003
Complementary CMR can detect prevalent subclinical myocardial involvement and regional dysfunction in systemic sclerosis patients without cardiac symptoms.
Kobayashi et al. (2016) conducted a cross-sectional in Systemic sclerosis without cardiac symptoms (n=25). Systemic sclerosis vs. Healthy controls was evaluated on Mean peak radial (Err) and circumferential (Ecc) strain (p=0.011 and 0.003). Systemic sclerosis patients without cardiac symptoms had significantly lower mean peak radial and circumferential strain compared to healthy controls (p=0.011 and p=0.003, respectively).
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