March 1, 1995Journal of the American College of CardiologyOpen Access

Electrocardiographic indexes of dispersion of ventricular repolarization: An isolated heart validation study

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Population

Isolated Langendorff-perfused rabbit hearts

Comparison

Measurement of new ECG indexes and standard… vs Direct measurement of dispersion of monophasic…

Design

Preclinical

Authors

MZMarkus ZabelElectrophysiology SPStuart PortnoyThe Medical Device (United Kingdom)MFMichael R. FranzElectrophysiology

Discussion

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Implication

Animal data suggest superior T-wave repolarization markers; leaves open human validation before clinical use.

Structured PICO

Population

Isolated Langendorff-perfused rabbit hearts

Intervention

Measurement of new ECG indexes (total T wave area, late T wave area, T peak to T end interval) and standard indexes (QT and JT dispersion)

Comparator

Direct measurement of dispersion of monophasic action potential duration at 90% repolarization (APD90) and dispersion of recovery time

Outcome

Correlation of ECG indexes with dispersion of APD90 and recovery timesurrogate

New ECG indexes including T peak to T end interval, total T wave area, and late T wave area correlate better with myocardial dispersion of repolarization than standard QT and JT dispersion in an isolated rabbit heart model.

Cite This Study

Zabel et al. (1995) studied this question.

synapsesocial.com/papers/69fc052d3a0f4cc134c8eeaa https://doi.org/10.1016/0735-1097(94)00446-w

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Electrocardiographic indexes of dispersion of ventricular repolarization: An isolated heart validation study

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Electrocardiographic indexes of dispersion of ventricular repolarization: An isolated heart validation study

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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