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May 11, 2026Biomedical Data Science0 citations

A Study of Cardiac Resynchronization Therapy (CRT) in Recalcitrant Heart Failure

SWShi Wenqi

Key Result

Cardiac resynchronization therapy reduced all-cause mortality by 36% compared to conventional treatment in patients with recalcitrant heart failure.

Structured PICO

Does cardiac resynchronization therapy improve outcomes in patients with recalcitrant heart failure?

P
Population
Patients with recalcitrant (refractory) heart failure
I
Intervention
Cardiac resynchronization therapy (CRT)
C
Comparator
Conventional drug therapy (including diuretics, ACEI/ARB, beta-blockers) or conventional pacemaker therapy

This review highlights that CRT significantly improves cardiac function, quality of life, and survival in recalcitrant heart failure compared to conventional medical therapy, while emphasizing the importance of patient selection and surgical technique.

Limitations

  • Difficulty of implanting left ventricular electrodes due to anatomical variations in 10-15% of patients
  • Electrode dislocation with an incidence of 1.7%-13.6%
  • Infection risk with an incidence of 1-2%
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Cite This Study

Shi Wenqi (2025) conducted a review in Recalcitrant heart failure. Cardiac resynchronization therapy (CRT) vs. Conventional treatment methods was evaluated. Cardiac resynchronization therapy reduced all-cause mortality by 36% compared to conventional treatment in patients with recalcitrant heart failure.

synapsesocial.com/papers/6a025f2ec9581ed855361d3chttps://doi.org/10.47297/wspbdswsp2752-630519.20250504
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