Key result
Concomitant PCI during TAVI is linked to ~66% worse two-year survival versus TAVI alone.
Why the study?
Does concomitant PCI worsen early and late clinical outcomes in elderly patients undergoing TAVI?
Population
411 elderly patients undergoing transcatheter aortic valve implantation (TAVI), mean age 82 years.
Comparison
Concomitant percutaneous coronary intervention… vs TAVI alone without concomitant PCI (n=346).
Design
Cohort
Follow-up
30 days and 2 years
Authors
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Supports caution with concomitant PCI during TAVI; leaves open whether staged PCI improves outcomes in randomized trials.
Cohort (n=411)
Does concomitant PCI worsen early and late clinical outcomes in elderly patients undergoing TAVI?
Absolute Event Rate: 15% vs 5%
p-value: p=0.01
Concomitant PCI with TAVI is associated with increased early and late mortality compared to TAVI alone in selected elderly patients.
Griese et al. (2014) conducted a cohort in Aortic valve disease and coronary artery disease (n=411). Concomitant percutaneous coronary intervention (PCI) and TAVI vs. TAVI alone was evaluated on 30-day mortality (p=0.01). Concomitant percutaneous coronary intervention during TAVI was associated with increased 30-day mortality (15% vs 5%; P=0.01) and poorer 2-year survival (OR 1.66; P=0.04) compared to TAVI alone.
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