Key result
Repeated measurements of heart rate and muscle sympathetic nerve activity demonstrated good short-term reliability (ICC 0.70-0.98) but lower long-term reliability (ICC 0.34-0.52) in normal subjects.
Population
7 normal subjects
Design
Cohort, All analyses were carried out blinded to subject and session
Follow-up
3 months
Authors
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Short-term MSNA and HR measures support acute autonomic research; long-term reliability remains limited, leaving optimal intervals for longitudinal studies open.
Observational (n=7)
Blinded analysis
Heart rate, MSNA, and their variability show good short-term reliability but lower long-term stability, with synchronous changes between absolute cardiovascular measures and their spectral components over time.
Borne et al. (1997) conducted an observational in Normal subjects (n=7). Repeated measurements of hemodynamics and MSNA was evaluated on Intraclass correlation coefficients (ICC) of short-term and long-term reliability of RR and MSNA. Repeated measurements of heart rate and muscle sympathetic nerve activity demonstrated good short-term reliability (ICC 0.70-0.98) but lower long-term reliability (ICC 0.34-0.52) in normal subjects.
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