Why the study?
Nitroglycerin is a first-line treatment for hypertensive AHFS, but nicardipine is also frequently used to treat hypertensive emergencies including AHFS.
Does nicardipine improve effectiveness compared to nitroglycerin in patients with hypertensive acute heart failure syndrome?
Does nicardipine improve effectiveness compared to nitroglycerin in patients with hypertensive acute heart failure syndrome?
Nicardipine was associated with faster BP control and shorter stays in hypertensive AHFS; leaves open whether it should supplant nitroglycerin pending RCTs.
Objective: Nitroglycerin is a first-line treatment for hypertensive acute heart failure syndrome (AHFS). However, nicardipine is frequently used to treat hypertensive emergencies, including AHFS. In this study, we compared the effectiveness of nicardipine and nitroglycerin in patients with hypertensive AHFS.
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Koroki et al. (2022) studied this question.
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