Why the study?
Does dilated cardiomyopathy increase left-to-right ventricular systolic interaction in a porcine model?
Population
12 pigs (6 normal, 6 with pacing-induced dilated cardiomyopathy resulting in congestive heart failure)
Comparison
Rapid withdrawal of blood from the LV apex into… vs Normal pigs undergoing the same procedure
Design
Preclinical
Follow-up
1 week (pacing duration)
Authors
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Greater LV-to-RV systolic interaction occurs in pacing-induced cardiomyopathy; leaves open its role in human dilated cardiomyopathy and RV failure.
Does dilated cardiomyopathy increase left-to-right ventricular systolic interaction in a porcine model?
Pacing-induced dilated cardiomyopathy significantly increases left-to-right ventricular systolic interaction, indicating an increased contribution of the left ventricle to right ventricular systolic pressure generation.
Farrar et al. (1993) studied this question.
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