Why the study?
Data are limited regarding the association between estimated plasma volume status determined using hemoglobin/hematocrit data and outcomes in patients with stable chronic heart failure.
Does higher estimated plasma volume status (ePVS) predict increased risk of all-cause mortality or heart failure rehospitalization in patients with stable chronic systolic heart failure?
Population
231 patients with stable CHF
Comparison
Three groups stratified by ePVS tertiles
Design
Prospective cohort study
Follow-up
Median 35.6 months
Authors
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ePVS may aid risk stratification in stable systolic HF; hypothesis-generating and requires prospective validation before practice change.
Does higher estimated plasma volume status (ePVS) predict increased risk of all-cause mortality or heart failure rehospitalization in patients with stable chronic systolic heart failure?
Estimated plasma volume status (ePVS) derived from hemoglobin and hematocrit is an independent prognostic marker for mortality and rehospitalization in patients with stable chronic systolic heart failure.
Lin et al. (2020) studied this question.