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January 1, 2022Global HeartOpen Access

High estimated plasma volume status significantly increased in-hospital mortality compared to low status in right heart failure patients (18.3% vs 6.7%; adjusted OR 5.83, 95% CI 1.62-20.95).

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Why the study?

Estimated plasma volume status has prognostic utility in left heart failure, but its use in right heart failure remains unknown.

Does high estimated plasma volume status (ePVS) predict in-hospital mortality in patients with isolated right heart failure?

Population

208 patients admitted for RHF

Comparison

High vs low estimated plasma volume status

Design

Retrospective cohort study

Follow-up

Median of 6 (3–19) days

Key result

High estimated plasma volume status significantly increased in-hospital mortality compared to low status in right heart failure patients (18.3% vs 6.7%; adjusted OR 5.83, 95% CI 1.62-20.95).

Authors

HSHannah SoetjoadiDFDewi FriskaBSBambang Budi Siswanto

Discussion

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Member takes

Overview

Suggests estimated plasma volume status may help risk-stratify right heart failure;.

Study Design

Type

Cohort (n=208)

Multicenter

No

Structured PICO

Does high estimated plasma volume status (ePVS) predict in-hospital mortality in patients with isolated right heart failure?

P
Population
208 patients admitted for isolated right heart failure, followed for a median of 6 days.
E
Exposure
High estimated plasma volume status (ePVS) calculated using the Hakim formula
C
Comparator
Low estimated plasma volume status (ePVS)
O
Outcome
In-hospital mortalityhard clinical

Main Result

Odds Ratio: 5.83 (95% CI 1.62–20.95)

Absolute Event Rate: 18.3% vs 6.7%

p-value: p=< 0.01

High estimated plasma volume status is a strong, low-cost predictor of in-hospital mortality in patients with isolated right heart failure.

Cite This Study

Soetjoadi et al. (2022) conducted a cohort in Right heart failure (n=208). High estimated plasma volume status (ePVS) vs. Low estimated plasma volume status (ePVS) was evaluated on In-hospital mortality (adjusted OR 5.83, 95% CI 1.62-20.95, p=< 0.01). High estimated plasma volume status significantly increased in-hospital mortality compared to low status in right heart failure patients (18.3% vs 6.7%; adjusted OR 5.83, 95% CI 1.62-20.95).

synapsesocial.com/papers/6a8d699a50db337a287dcc87https://doi.org/10.5334/gh.1136
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