Key result
Primary prostate carcinoma with hepatic metastasis presented with unexplained, inordinately elevated CK-MB levels despite normal total CK and no evidence of cardiac injury in a single patient.
Case Report (n=1)
Extremely high CK-MB levels can be observed in patients with prostate carcinoma and hepatic metastasis without any underlying cardiac injury.
CK-MB elevation may not signal cardiac injury in prostate cancer with metastases; leaves open tumor marker role for validation.
Creatine kinase-MB (CK-MB) is a widely evaluated testing enzyme in diseases related to cardiac or injury.Here we relate a clinical scenario of a patient presenting with no chest pain or symptom related to the cardiac disease whose CK-MB levels were remained inordinately elevated despite normal total CK levels.Clinically and subsequent pathological examination showed no evidence of infarction, inflammation or cardiac ischemia.Further evaluation of the patient reveals the presence of the primary prostate carcinoma with the secondary metastatic lesions in the hepatic lobe.
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Anurag Yadav (2008) conducted a case report in Prostate carcinoma with elevated CK-MB (n=1). Primary prostate carcinoma with hepatic metastasis presented with unexplained, inordinately elevated CK-MB levels despite normal total CK and no evidence of cardiac injury in a single patient.
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